Treatment for Stalled Radiation Head Wound
William Pace, MD
Jefferson Frankford and Jefferson Bucks Hospitals, Philadelphia
- In January 2020, a 77-year-old male presented with a large (11cm x 14cm) radiation wound at top of his head after finishing radiation therapy in December 2019.
- Wound had been open for 1 month, and patient was in constant and severe pain.
- Wound was especially sensitive to touch, and no pain treatment was effective.
- Dressing changes took 45 minutes to an hour and involved multiple clinicians taking turns to slowly remove the dressing.
- Patient had difficulty sleeping.
- ADAPTIC TOUCH™
Procedure & Treatment
- Scalp was irradiated and debrided for second intention healing.
- Microlyte® Matrix was then tiled over the entire surface of wound, then covered with ADAPTIC TOUCH™
- Microlyte and ADAPTIC TOUCH™ were reapplied on day 3.
- Patient was then assessed on day 4, day 14, then weekly until week 16.
- After just 4 days of Microlyte® treatment, the patient’s wound decreased from 11cm x 14cm to 8.5cm x 10.5cm, a 42% reduction.
- Patient reported slight pain at dressing removal, and no pain at all during and after Microlyte® application.
- Patient was able to sleep for the first time in months.
- Importantly, the wound did not become infected.
- On day 14, wound tissue showed increased granulation and decreased exudate.
- At 16 weeks, the wound decreased to 3.5 cm x 4 cm, a 91% reduction from day 1.
- Post-irradiated tissue over a large surface area is notoriously difficult to treat and is prone to infection.
- Radiation wounds often turn into chronic ulcers, because of difficulty containing radiation treatment to malignant cells without damaging surrounding healthy cells.
- In this case study, we demonstrate that Microlyte® was able to close a large radiation wound by 42% in 4 days after previous treatment failed to close patient’s wound.
- In addition to efficacy, Microlyte® use was painless and allowed the patient to sleep, thereby increasing his quality of life.
- Microlyte® and ADAPTIC TOUCH™ worked together to jump-start patient’s wound-healing process and shows promise in treating difficult-to-treat radiation chronic ulcers.
(A) DAY 1
(B) DAY 1
(C) DAY 4
(D) DAY 14
(E) Week 16
Figure 1: Patient presented with an excised scalp wound that was irradiated and debrided for second intention (A). Microlyte® was applied over the entire surface of wound (B), and then reapplied on the 3rd day (figure not shown). Wound closed 42% over 4 days (C) and demonstrated new granulation tissue and decreased exudate on day 14 (D). At 16 weeks, the wound decreased to 3.5 cm x 4 cm, A 91% reduction from day 1 (E).