Healthcare Professional FAQs
When you sign up for the Microlyte Challenge, Imbed Biosciences will supply you (free of charge) enough Microlyte® Matrix or Microlyte® Surgical to treat an acute, chronic, or surgical wound. All we ask for in exchange is your feedback during and after the treatment. Sign up here: Microlyte Challenge
Microlyte® Matrix should be covered with a non-adherent dressing and any other dressings needed to maintain a moist wound environment. Change the cover dressing as needed to maintain a moist wound environment or when Microlyte®Matrix is reapplied.
Absolutely. Microlyte® Matrix should be cut to size slightly larger than the wound. Multiple pieces may be used to cover the wound bed and the wound margin.
We recommend that a dry wound be moistened with sterile saline after routine debridement and prior to application of Microlyte® Matrix
Reapply Microlyte® Matrix depending on the wound and the healing progression, or when clinically indicated. To reapply, carefully remove the cover dressing(s). Gently irrigate wound with sterile saline to remove necrotic tissue. It is not necessary to remove any residual Microlyte® Matrix observed during cover dressing changes.
Once Microlyte® Matrix is applied to the wound bed, the matrix essentially becomes one with the wound. As it is fully resorbable, there is no need to actively remove the product from the wound bed prior to reapplication. If removal is necessary, Microlyte® Matrix can be removed by gentle irrigation with sterile saline.
No. Because of the conformal nature of Microlyte® Matrix, it contains a very low amount of silver that is still effective on most types of common wound microbes.
Yes, Microlyte® Matrix has been demonstrated compatible with magnetic resonance imaging.
Microlyte® Matrix facilitates healing in acute and chronic wounds through the matrix function of the PEM nanofilm. The PEM component of Microlyte® Matrix contains both anionic and cationic charged polymeric components which serve to shield approaching granulation cells from the generally disorganized surface chemistry common to wound beds. This masking provides a functional molecular matrix or template to facilitate the granulation process in the healing wound. The ultrathin formfactor of Microlyte® Matrix allows it to rapidly absorb wound fluid and transform into a bioresorbable material that intimately contours to the underlying wound bed. This places the matrix directly on the wound bed where it is most beneficial to the healing process. The hydrophilic resorbable polyvinyl alcohol (PVA) in Microlyte® Matrix maintains a physiologically moist microenvironment in the wound, which further facilitates wound healing.
The ultrathin form factor of Microlyte® Matrix is actually the key. It allows Microlyte® Matrix to conform tightly to the wound bed and brings the matrix functionality to the “nooks and crannies” of the wound. Comparatively bulky macro-scale matrices sit well above the wound bed and force the granulation cells to come to them.
Is Microlyte® Matrix active against resistant microorganisms such as Methicillin Resistant Staphylococcus aureus (MRSA) or Vancomycin Resistant Enterococcus (VRE)?
Microlyte® Matrix has been demonstrated in vitro to be effective against a number of micro organisms including:
Methicillin Resistant Staphylococcus aureus (MRSA)
Vancomycin Resistant Enterococcus (VRE)
- Klebsiella pneumoniae
- Staphylococcus aureus
- Escherichia coli
- Candida tropicalis
- Candida albicans
Many agents or solutions have been traditionally used to cleanse wounds. We have tested Microlyte® Matrix specifically with hypochlorous acid cleansers and found them to be compatible.
Yes, Microlyte® Matrix may be overlapped without any concern.
Microlyte® Matrix may a role in preventing infection on post-operative wounds in acute settings. It has been used as a prophylactic to prevent post-operative infection in high-risk patients, who may get exposed to bacterial or infection causing organisms during their surgery, or who may be susceptible to infection. For these types of patients, the prevention of infection is a key requirement for the wound healing process. Additionally, it is recognized that open wounds that are not clinically infected can be heavily colonized, thus impairing wound healing. Microlyte® Matrix is promoted for the management of more heavily colonised non-infected chronic and acute wounds.