When you sign up for the Microlyte 30 Day Challenge, Imbed Biosciences will supply you (free of charge) enough Microlyte® Matrix to treat one of your most difficult wounds for 30 days. All we ask for in exchange is your feedback during and after the 30-day treatment. Sign up here: https://microlytematrix.com/30-day-challenge/
We recommend you use the dressing you would use for moisture management in the absence of Microlyte® Matrix.
We recommend that a dry wound be moistened with sterile saline or water after routine debridement and prior to application of Microlyte® Matrix
We recommend replacing the Microlyte® Matrix product with each secondary dressing change, as called for by the volume of wound exudate. Highly exuding wounds will require more frequent secondary dressing changes along with Microlyte® Matrix reapplication.
Because Microlyte® Matrix is fully resorbable, there is no need to actively remove the product from the wound bed prior to reapplication. If removal is necessary, Microlyte® Matrix can be removed by gentle irrigation with sterile saline.
Microlyte® Matrix provides active antimicrobial silver in the wound bed for up to 3 days.
No. Because of the conformal nature of Microlyte® Matrix, it contains a much lower amount of silver than other silver-based creams and dressings.
Absolutely. Microlyte® Matrix can be trimmed to the wound size before or after placement in the wound. Irregularly-shaped wounds can be covered with trimmed pieces by “tiling” across the wound.
Microlyte® Matrix is a thin polymeric film which absorbs moisture in the wound bed and contours intimately with the wound surface. Because of this conformal nature, Microlyte® Matrix can be highly effective in killing microbes that remain in the wound even after surgical debridement. This allows the wound to proceed out of the inflammatory phase and resume the normal healing process.
With respect to other silver products, the biggest differentiator is the form factor. Microlyte® Matrix is a thin polymeric film which hydrates rapidly and conforms tightly to the wound bed. The conformal nature of Microlyte® Matrix means that the lower level of silver can be highly effective against microbes in the wound. Because there is less silver in Microlyte® Matrix than other products, there is less residual toxicity to healthy tissues. Finally, and perhaps most importantly, Microlyte® Matrix deposits a resorbable polyelectrolyte nanofilm in the wound which masks the disorganized surface chemistry of the wound bed and presents a uniform matrix for incoming fibroblasts and granulation tissue.
Microlyte® Matrix has been demonstrated in vitro to be effective against a number of micro organisms including:
Methicillin Resistant Staphylococcus aureus (MRSA)
Vancomycin Resistant Enterococcus (VRE)
- Klebsiella pneumoniae
- Staphylococcus aureus
- Escherichia coli
- Candida tropicalis
- Candida albicans
Many agents or solutions have been traditionally used to cleanse burn wounds. We have tested Microlyte® Matrix specifically with hypochlorous acid cleansers and found them to be compatible. Generally speaking, if the agent does not contain an oil base or leave a residue, it may be used to cleanse the wound.
Yes, Microlyte® Matrix may be overlapped without any concern.
Yes, Microlyte® Matrix has been demonstrated compatible with magnetic resonance imaging.
The ultrathin form factor of Microlyte® Matrix is the key. It is able conform tightly to the wound bed and exert antimicrobial activity on the microorganisms hiding in the “nooks and crannies” of the wound. Comparatively, traditional silver dressings serve as crude reservoirs of silver that sit well above the wound bed. Most of the silver released by these dressings gets inactivated in the wound fluid.
Microlyte® Matrix may a role in preventing infection on post-operative wounds in acute settings. It has been used as a prophylactic to prevent post-operative infection in high-risk patients, who may get exposed to bacterial or infection causing organisms during their surgery, or who may be susceptible to infection. For these types of patients, the prevention of infection is a key requirement for the wound healing process. Additionally, it is recognized that open wounds that are not clinically infected can be heavily colonized, thus impairing wound healing. Microlyte® Matrix is promoted for the management of more heavily colonised non-infected chronic and acute wounds.