Microlyte® Matrix facilitates healing in acute and chronic wounds through the matrix function of the PEM nanofilm. The PEM component of Microlyte® Matrix contains both anionic and cationic charged polymeric components which serve to shield approaching granulation cells from the generally disorganized surface chemistry common to wound beds. This masking provides a functional molecular matrix or template to facilitate the granulation process in the healing wound. The ultrathin formfactor of Microlyte® Matrix allows it to rapidly absorb wound fluid and transform into a bioresorbable material that intimately contours to the underlying wound bed. This places the matrix directly on the wound bed where it is most beneficial to the healing process. The hydrophilic resorbable polyvinyl alcohol (PVA) in Microlyte® Matrix maintains a physiologically moist microenvironment in the wound, which further facilitates wound healing.