Microlyte® Matrix provides just the right combination of a synthetic wound matrix and moisture management to facilitate healing in acute and chronic wounds. Microlyte® Matrix comprises a polyelectrolyte multilayer (PEM) nanofilm of cationic and anionic polymers, which together act as a functional molecular template to facilitate the granulation in the wound bed. The nanofilm matrix is coated with a 20-micron layer of resorbable polyvinyl alcohol (PVA) to provide moisture management and product handleability. The nanofilm matrix contains a low level of ionic and metallic silver (<25µg/sq cm) to prevent microbial contamination and colonization of the matrix. Reduction of bacterial bioburden may reduce microbial colonization and risks of wound infection.