Next Generation Antimicrobial Matrix

Microlyte® Matrix absorbs wound fluid and transforms into a bioresorbable gel that intimately contours to the underlying wound bed. It maintains a physiologically moist microenvironment. In vitro and in vivo, studies indicate that components of the matrix allow cell growth and neovascularization. 1,2,3

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Bioresorbable Matrix

100% bioresorbable polymer matrix eliminates the need to remove residual matrix from the wound2

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Contours to Wound Bed

Absorbs wound fluid and serves as scaffold for cell migration, vascularization, granulation tissue formation1,2

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Transparent & Synthetic

Allows for clear view of wound bed, isn’t of human or animal origin, and holds a long room-temp. shelf life6

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Low Residual Toxicity

Less wound staining and needs only ˜1 µg/cm² Ag+ to kill microbes on the tissue surface7

Clinically-Proven

Thirty-two patients with a total of 35 chronic, nonhealing wounds of varying types were treated with Microlyte® Matrix once every three days.  At 3 weeks, 72% of wounds had significantly improved healing with an average wound area reduction of 66%. By 12 weeks, 91% of wounds either healed completely or improved significantly with an average wound area reduction of 73%.  The application of Microlyte® Matrix was safe and well tolerated, and it facilitated improvements in healing of a majority of the complex chronic wounds studied.  Click below to read the full article from the November issue of WOUNDS.

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Surgical Background Image Dr. Angela Gibson “The property that I find unique in Microlyte is the total conformation to the wound bed as the thin film melts into all the crevices of a wound likely where the bacteria are hiding and preventing healing. It is also very easy to apply and may decrease irritation, such as itching, caused by other products.” Angela Gibson, MD, PhD, FACS Burn Surgeon and Medical Director UW Health Surgical Background Image Dr. _Jeffrey Niezgoda “We like using this a lot, especially in wounds that have an irregular surface. It conforms to the wound base very readily. The multi-day antimicrobial effect is nice for wounds that may require compression or a secondary dressing that we don’t want to change everyday.” Jeffrey A. Niezgoda, MD President and Medical Director AZH Wound and Vascular Surgical Background Image Michael Schurr “Microlyte Matrix employs 50 to 100 times less silver than the traditional silver products used in prior protocols of care for wounds, yet it is still more effective in healing chronic wounds. It is very encouraging to get such promising outcomes in deteriorating and stagnant wounds by switching to Microlyte® Matrix as the primary antimicrobial dressing.” Michael Schurr, MD, Imbed Co-Founder Chair of General Surgery at Mountain Area Health Education Center, Asheville, NC

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REFERENCES 1 A Agarwal, et al. Biomaterials, 31 (4), 680-690, 2010. 2 Systemic Toxicity, Local Tissue Response, and Wound Healing Study of Microlyte Ag wound dressing, Following Repeated Treatment to Full-Thickness Wounds in Rats – 28 Days. Study 15T_41113_02, 2015. Data on file, Imbed Biosciences. 3 MTT cytotoxicity testing conducted at NAMSA. Data on file at Imbed Biosciences. 4 FDA 510k application. Data on file, Imbed Biosciences. 5 As demonstrated in vitro